2at6

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Current revision (07:29, 23 August 2023) (edit) (undo)
 
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<StructureSection load='2at6' size='340' side='right'caption='[[2at6]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
<StructureSection load='2at6' size='340' side='right'caption='[[2at6]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2at6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AT6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2at6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AT6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.22&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2at4|2at4]], [[2at5|2at5]], [[1x8q|1x8q]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDE:FE(III)+DEUTEROPORPHYRIN+IX'>FDE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2at6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at6 OCA], [https://pdbe.org/2at6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2at6 RCSB], [https://www.ebi.ac.uk/pdbsum/2at6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2at6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2at6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at6 OCA], [https://pdbe.org/2at6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2at6 RCSB], [https://www.ebi.ac.uk/pdbsum/2at6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2at6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Rhopr]]
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[[Category: Rhodnius prolixus]]
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[[Category: Amoia, A M]]
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[[Category: Amoia AM]]
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[[Category: Montfort, W R]]
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[[Category: Montfort WR]]
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[[Category: Beta barrel]]
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[[Category: Ferric]]
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[[Category: Heme analog]]
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[[Category: Lipocalin]]
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[[Category: Transport protein]]
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Current revision

1.22 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Containing Fe(III) Deuteroporphyrin IX Complexed With Water at pH 5.6

PDB ID 2at6

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