2at8
From Proteopedia
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<StructureSection load='2at8' size='340' side='right'caption='[[2at8]], [[Resolution|resolution]] 1.00Å' scene=''> | <StructureSection load='2at8' size='340' side='right'caption='[[2at8]], [[Resolution|resolution]] 1.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2at8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2at8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AT8 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDD:FE(III)+2,4-DIMETHYL+DEUTEROPORPHYRIN+IX'>FDD</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDD:FE(III)+2,4-DIMETHYL+DEUTEROPORPHYRIN+IX'>FDD</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2at8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at8 OCA], [https://pdbe.org/2at8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2at8 RCSB], [https://www.ebi.ac.uk/pdbsum/2at8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2at8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2at8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2at8 OCA], [https://pdbe.org/2at8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2at8 RCSB], [https://www.ebi.ac.uk/pdbsum/2at8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2at8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Rhodnius prolixus]] |
| - | [[Category: Amoia | + | [[Category: Amoia AM]] |
| - | [[Category: Montfort | + | [[Category: Montfort WR]] |
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Revision as of 07:29, 23 August 2023
0.96 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Containing Fe(III) 2,4 Dimethyl Deuteroporphyrin IX Complexed With Nitric Oxide at pH 5.6
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