2esa
From Proteopedia
(Difference between revisions)
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<StructureSection load='2esa' size='340' side='right'caption='[[2esa]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2esa' size='340' side='right'caption='[[2esa]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2esa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2esa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ESA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDM:GELDANAMYCIN'>GDM</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | < | + | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2esa OCA], [https://pdbe.org/2esa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2esa RCSB], [https://www.ebi.ac.uk/pdbsum/2esa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2esa ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2esa OCA], [https://pdbe.org/2esa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2esa RCSB], [https://www.ebi.ac.uk/pdbsum/2esa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2esa ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Canis lupus familiaris]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Gewirth | + | [[Category: Gewirth DT]] |
| - | + | [[Category: Immormino RM]] | |
| - | [[Category: Immormino | + | [[Category: Metzger IV LE]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA
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