2xl4

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Current revision (08:01, 23 August 2023) (edit) (undo)
 
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<StructureSection load='2xl4' size='340' side='right'caption='[[2xl4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2xl4' size='340' side='right'caption='[[2xl4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xl4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XL4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xl4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XL4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lntA, lmo0438 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1639 "Bacterium monocytogenes hominis" Nyfeldt 1932])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xl4 OCA], [https://pdbe.org/2xl4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xl4 RCSB], [https://www.ebi.ac.uk/pdbsum/2xl4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xl4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xl4 OCA], [https://pdbe.org/2xl4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xl4 RCSB], [https://www.ebi.ac.uk/pdbsum/2xl4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xl4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LNTA_LISMO LNTA_LISMO]] Relieves the repression of host cell immune response genes (interferon-stimulated genes) by blocking the recruitment of host BAHD1 to these genes. May modulate interferon-mediated immune response to control bacterial colonization of the host.
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[https://www.uniprot.org/uniprot/LNTA_LISMO LNTA_LISMO] Relieves the repression of host cell immune response genes (interferon-stimulated genes) by blocking the recruitment of host BAHD1 to these genes. May modulate interferon-mediated immune response to control bacterial colonization of the host.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bierne, H]]
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[[Category: Listeria monocytogenes EGD-e]]
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[[Category: Cabanes, D]]
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[[Category: Bierne H]]
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[[Category: Camejo, A]]
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[[Category: Cabanes D]]
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[[Category: Cossart, P]]
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[[Category: Camejo A]]
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[[Category: Dessen, A]]
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[[Category: Cossart P]]
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[[Category: Job, V]]
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[[Category: Dessen A]]
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[[Category: Lebreton, A]]
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[[Category: Job V]]
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[[Category: Mattei, P J]]
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[[Category: Lebreton A]]
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[[Category: Regnault, B]]
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[[Category: Mattei PJ]]
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[[Category: Tham, T N]]
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[[Category: Regnault B]]
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[[Category: Immune system]]
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[[Category: Tham TN]]
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[[Category: Toxin]]
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Current revision

LntA, a virulence factor from Listeria monocytogenes

PDB ID 2xl4

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