5i14

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Current revision (08:19, 23 August 2023) (edit) (undo)
 
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<StructureSection load='5i14' size='340' side='right'caption='[[5i14]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='5i14' size='340' side='right'caption='[[5i14]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5i14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I14 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5I14 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5i14]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I14 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.745&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5i14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i14 OCA], [http://pdbe.org/5i14 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i14 RCSB], [http://www.ebi.ac.uk/pdbsum/5i14 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i14 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i14 OCA], [https://pdbe.org/5i14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i14 RCSB], [https://www.ebi.ac.uk/pdbsum/5i14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i14 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt4]]
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[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Boura, E]]
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[[Category: Boura E]]
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[[Category: Klima, M]]
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[[Category: Klima M]]
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[[Category: Hydrolase]]
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[[Category: T4 lysozyme]]
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Current revision

Truncated and mutated T4 lysozyme

PDB ID 5i14

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OCA

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