2fh7

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Current revision (09:26, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2fh7' size='340' side='right'caption='[[2fh7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2fh7' size='340' side='right'caption='[[2fh7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fh7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FH7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fh7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FH7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPRS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fh7 OCA], [https://pdbe.org/2fh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2fh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fh7 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2fh7 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fh7 OCA], [https://pdbe.org/2fh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2fh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fh7 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2fh7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PTPRS_HUMAN PTPRS_HUMAN]] Interacts with LAR-interacting protein LIP.1.
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[https://www.uniprot.org/uniprot/PTPRS_HUMAN PTPRS_HUMAN] Interacts with LAR-interacting protein LIP.1.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C]]
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[[Category: Alvarado J]]
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[[Category: Alvarado, J]]
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[[Category: Atwell S]]
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[[Category: Atwell, S]]
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[[Category: Bain KT]]
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[[Category: Bain, K T]]
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[[Category: Burley SK]]
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[[Category: Burley, S K]]
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[[Category: Freeman JC]]
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[[Category: Freeman, J C]]
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[[Category: Kearins MC]]
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[[Category: Kearins, M C]]
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[[Category: Koss J]]
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[[Category: Koss, J]]
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[[Category: Maletic M]]
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[[Category: Maletic, M]]
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[[Category: Ozyurt S]]
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[[Category: Structural genomic]]
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[[Category: Powell A]]
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[[Category: Ozyurt, S]]
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[[Category: Rooney I]]
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[[Category: Powell, A]]
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[[Category: Russell M]]
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[[Category: Rooney, I]]
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[[Category: Sauder JM]]
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[[Category: Russell, M]]
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[[Category: Smith D]]
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[[Category: Sauder, J M]]
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[[Category: Thompson DA]]
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[[Category: Smith, D]]
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[[Category: Udupi R]]
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[[Category: Thompson, D A]]
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[[Category: Wasserman SR]]
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[[Category: Udupi, R]]
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[[Category: Wasserman, S R]]
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[[Category: Dual domain phosphatase]]
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[[Category: Hydrolase]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Receptor protein tyrosine phosphatase]]
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Current revision

Crystal structure of the phosphatase domains of human PTP SIGMA

PDB ID 2fh7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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