2fj2

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<StructureSection load='2fj2' size='340' side='right'caption='[[2fj2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2fj2' size='340' side='right'caption='[[2fj2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fj2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fj2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ2 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [https://pdbe.org/2fj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj2 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj2 OCA], [https://pdbe.org/2fj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj2 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P]] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human herpesvirus 8 strain GK18]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cao, R]]
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[[Category: Cao R]]
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[[Category: Dong, C Z]]
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[[Category: Dong CZ]]
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[[Category: Gao, Y G]]
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[[Category: Gao YG]]
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[[Category: Huang, Z]]
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[[Category: Huang Z]]
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[[Category: Kumar, S]]
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[[Category: Kumar S]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Liu, D]]
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[[Category: Liu D]]
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[[Category: Wilson, S R]]
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[[Category: Wilson SR]]
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[[Category: Anti-hiv]]
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[[Category: Chemokine]]
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[[Category: Herpesvirus]]
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Revision as of 09:27, 30 August 2023

Crystal Structure of Viral Macrophage Inflammatory Protein-II

PDB ID 2fj2

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