2he3
From Proteopedia
(Difference between revisions)
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<StructureSection load='2he3' size='340' side='right'caption='[[2he3]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2he3' size='340' side='right'caption='[[2he3]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2he3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2he3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HE3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2he3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2he3 OCA], [https://pdbe.org/2he3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2he3 RCSB], [https://www.ebi.ac.uk/pdbsum/2he3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2he3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2he3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2he3 OCA], [https://pdbe.org/2he3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2he3 RCSB], [https://www.ebi.ac.uk/pdbsum/2he3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2he3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GPX2_HUMAN GPX2_HUMAN] Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Johansson C]] |
| - | [[Category: Johansson | + | [[Category: Kavanagh KL]] |
| - | [[Category: Kavanagh | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Rojkova A]] |
| - | [[Category: Rojkova | + | [[Category: Sundstrom M]] |
| - | + | [[Category: Weigelt J]] | |
| - | [[Category: Sundstrom | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: | + | |
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Current revision
Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
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