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2hlp

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Current revision (09:59, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2hlp' size='340' side='right'caption='[[2hlp]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='2hlp' size='340' side='right'caption='[[2hlp]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2hlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"halobacterium_marismortui"_elazari-volcani_1957 "halobacterium marismortui" elazari-volcani 1957]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HLP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2hlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HLP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlp OCA], [https://pdbe.org/2hlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hlp RCSB], [https://www.ebi.ac.uk/pdbsum/2hlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hlp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlp OCA], [https://pdbe.org/2hlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hlp RCSB], [https://www.ebi.ac.uk/pdbsum/2hlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hlp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MDH_HALMA MDH_HALMA]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
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[https://www.uniprot.org/uniprot/MDH_HALMA MDH_HALMA] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_00487]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Halobacterium marismortui elazari-volcani 1957]]
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[[Category: Haloarcula marismortui]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Malate dehydrogenase]]
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[[Category: Garcin E]]
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[[Category: Garcin, E]]
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[[Category: Madern D]]
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[[Category: Madern, D]]
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[[Category: Richard SB]]
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[[Category: Richard, S B]]
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[[Category: Zaccai G]]
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[[Category: Zaccai, G]]
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[[Category: Halophilic]]
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[[Category: Ion-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Salt bridge]]
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Current revision

CRYSTAL STRUCTURE OF THE E267R MUTANT OF A HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM

PDB ID 2hlp

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OCA

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