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2hqe

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Current revision (10:00, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2hqe' size='340' side='right'caption='[[2hqe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2hqe' size='340' side='right'caption='[[2hqe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2hqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2hqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQE FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hqx|2hqx]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SND1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqe OCA], [https://pdbe.org/2hqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqe RCSB], [https://www.ebi.ac.uk/pdbsum/2hqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqe ProSAT], [https://www.topsan.org/Proteins/SECSG/2hqe TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqe OCA], [https://pdbe.org/2hqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqe RCSB], [https://www.ebi.ac.uk/pdbsum/2hqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqe ProSAT], [https://www.topsan.org/Proteins/SECSG/2hqe TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN]] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
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[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cheng, C]]
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[[Category: Cheng C]]
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[[Category: Liu, Z J]]
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[[Category: Liu ZJ]]
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[[Category: Structural genomic]]
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[[Category: Shah N]]
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[[Category: Shah, N]]
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[[Category: Silvennoinen O]]
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[[Category: Silvennoinen, O]]
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[[Category: Wang BC]]
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[[Category: Wang, B C]]
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[[Category: Xu H]]
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[[Category: Xu, H]]
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[[Category: Yang J]]
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[[Category: Yang, J]]
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[[Category: Zhao M]]
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[[Category: Zhao, M]]
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[[Category: Large fragment]]
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[[Category: P100 tudor domain]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Secsg]]
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[[Category: Transcription]]
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Current revision

Crystal structure of human P100 Tudor domain: Large fragment

PDB ID 2hqe

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