2hrd
From Proteopedia
(Difference between revisions)
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<StructureSection load='2hrd' size='340' side='right'caption='[[2hrd]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2hrd' size='340' side='right'caption='[[2hrd]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2hrd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2hrd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HRD FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TDR:THYMINE'>TDR</scene></td></tr> |
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| - | < | + | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hrd OCA], [https://pdbe.org/2hrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hrd RCSB], [https://www.ebi.ac.uk/pdbsum/2hrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hrd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hrd OCA], [https://pdbe.org/2hrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hrd RCSB], [https://www.ebi.ac.uk/pdbsum/2hrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hrd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] |
| - | + | [[Category: Gabdulkhakov AG]] | |
| - | [[Category: Gabdulkhakov | + | [[Category: Mikhailov AM]] |
| - | [[Category: Mikhailov | + | [[Category: Timofeev VI]] |
| - | [[Category: Timofeev | + | |
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| - | + | ||
Current revision
Crystal structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymine and phosphate ion at 1.70A resolution
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