2nzj

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Current revision (10:27, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2nzj' size='340' side='right'caption='[[2nzj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2nzj' size='340' side='right'caption='[[2nzj]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nzj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nzj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">REM1, GES, REM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzj OCA], [https://pdbe.org/2nzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzj RCSB], [https://www.ebi.ac.uk/pdbsum/2nzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzj OCA], [https://pdbe.org/2nzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzj RCSB], [https://www.ebi.ac.uk/pdbsum/2nzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/REM1_HUMAN REM1_HUMAN]] Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
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[https://www.uniprot.org/uniprot/REM1_HUMAN REM1_HUMAN] Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Berridge, G]]
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[[Category: Berridge G]]
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[[Category: Bray, J]]
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[[Category: Bray J]]
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[[Category: Burgess, N]]
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[[Category: Burgess N]]
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[[Category: Delft, F von]]
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[[Category: Doyle D]]
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[[Category: Doyle, D]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Elkins JM]]
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[[Category: Elkins, J M]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O]]
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[[Category: Gorrec F]]
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[[Category: Gorrec, F]]
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[[Category: Johansson C]]
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[[Category: Johansson, C]]
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[[Category: Marsden B]]
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[[Category: Marsden, B]]
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[[Category: Papagrigoriou E]]
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[[Category: Papagrigoriou, E]]
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[[Category: Salah E]]
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[[Category: Structural genomic]]
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[[Category: Soundararajan M]]
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[[Category: Salah, E]]
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[[Category: Sundstrom M]]
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[[Category: Soundararajan, M]]
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[[Category: Turnbull AP]]
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[[Category: Sundstrom, M]]
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[[Category: Ugochukwu E]]
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[[Category: Turnbull, A P]]
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[[Category: Umeano C]]
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[[Category: Ugochukwu, E]]
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[[Category: Watts S]]
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[[Category: Umeano, C]]
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[[Category: Weigelt J]]
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[[Category: Watts, S]]
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[[Category: Yang X]]
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[[Category: Weigelt, J]]
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[[Category: Von Delft F]]
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[[Category: Yang, X]]
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[[Category: Gdp/gtp binding]]
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[[Category: Gtp hydrolysis]]
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[[Category: Rad and gem like gtp binding protein 1]]
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[[Category: Rem1]]
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[[Category: Sgc]]
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[[Category: Signaling protein]]
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Current revision

The crystal structure of REM1 in complex with GDP

PDB ID 2nzj

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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