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2nzl
From Proteopedia
(Difference between revisions)
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<StructureSection load='2nzl' size='340' side='right'caption='[[2nzl]], [[Resolution|resolution]] 1.35Å' scene=''> | <StructureSection load='2nzl' size='340' side='right'caption='[[2nzl]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2nzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2nzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZL FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GLV:GLYOXYLIC+ACID'>GLV</scene></td></tr> | |
| - | <tr id=' | + | |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzl OCA], [https://pdbe.org/2nzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzl RCSB], [https://www.ebi.ac.uk/pdbsum/2nzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzl OCA], [https://pdbe.org/2nzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzl RCSB], [https://www.ebi.ac.uk/pdbsum/2nzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Berridge | + | [[Category: Berridge G]] |
| - | [[Category: Debreczeni | + | [[Category: Debreczeni JE]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Kavanagh K]] |
| - | [[Category: Kavanagh | + | [[Category: Niesen F]] |
| - | [[Category: Niesen | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Papagrigoriou E]] |
| - | [[Category: Papagrigoriou | + | [[Category: Pilka E]] |
| - | [[Category: Pilka | + | [[Category: Sundstrom M]] |
| - | + | [[Category: Turnbull A]] | |
| - | [[Category: Sundstrom | + | [[Category: Ugochukwu E]] |
| - | [[Category: Turnbull | + | [[Category: Weigelt J]] |
| - | [[Category: Ugochukwu | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: | + | |
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Current revision
Crystal structure of human hydroxyacid oxidase 1
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berridge G | Debreczeni JE | Edwards A | Gileadi O | Kavanagh K | Niesen F | Oppermann U | Papagrigoriou E | Pilka E | Sundstrom M | Turnbull A | Ugochukwu E | Weigelt J | Von Delft F
