2oby
From Proteopedia
(Difference between revisions)
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<StructureSection load='2oby' size='340' side='right'caption='[[2oby]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2oby' size='340' side='right'caption='[[2oby]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2oby]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2oby]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OBY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oby OCA], [https://pdbe.org/2oby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oby RCSB], [https://www.ebi.ac.uk/pdbsum/2oby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oby ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oby OCA], [https://pdbe.org/2oby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oby RCSB], [https://www.ebi.ac.uk/pdbsum/2oby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oby ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/QORX_HUMAN QORX_HUMAN] May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).<ref>PMID:19349281</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Debreczeni | + | [[Category: Debreczeni J]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Farres J]] |
| - | [[Category: Farres | + | [[Category: Fita I]] |
| - | [[Category: Fita | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Haroniti A]] |
| - | [[Category: Haroniti | + | [[Category: Johansson C]] |
| - | [[Category: Johansson | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Pares X]] |
| - | [[Category: Pares | + | [[Category: Pike ACW]] |
| - | [[Category: Pike | + | [[Category: Porte S]] |
| - | [[Category: Porte | + | [[Category: Shafqat N]] |
| - | [[Category: Shafqat | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Valencia E]] |
| - | [[Category: Valencia | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
Current revision
Crystal structure of Human P53 inducible oxidoreductase (TP53I3,PIG3)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Debreczeni J | Edwards A | Farres J | Fita I | Gileadi O | Haroniti A | Johansson C | Oppermann U | Pares X | Pike ACW | Porte S | Shafqat N | Sundstrom M | Valencia E | Weigelt J | Von Delft F
