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2oy2

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Current revision (10:50, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2oy2' size='340' side='right'caption='[[2oy2]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2oy2' size='340' side='right'caption='[[2oy2]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2oy2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OY2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2oy2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OY2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bzs|1bzs]], [[2oy4|2oy4]], [[2oxu|2oxu]], [[2oxw|2oxw]], [[2oxz|2oxz]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP8, CLG1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oy2 OCA], [https://pdbe.org/2oy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oy2 RCSB], [https://www.ebi.ac.uk/pdbsum/2oy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oy2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oy2 OCA], [https://pdbe.org/2oy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oy2 RCSB], [https://www.ebi.ac.uk/pdbsum/2oy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oy2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN]] Can degrade fibrillar type I, II, and III collagens.
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[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Neutrophil collagenase]]
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[[Category: Bertini I]]
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[[Category: Bertini, I]]
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[[Category: Calderone V]]
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[[Category: Calderone, V]]
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[[Category: Fragai M]]
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[[Category: Fragai, M]]
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[[Category: Luchinat C]]
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[[Category: Luchinat, C]]
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[[Category: Maletta M]]
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[[Category: Maletta, M]]
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[[Category: Yeo KJ]]
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[[Category: Yeo, K J]]
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[[Category: Hydrolase]]
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[[Category: Matrix metalloproteinase]]
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[[Category: Mmp-8]]
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Current revision

Human MMP-8 in complex with peptide IAG

PDB ID 2oy2

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