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2px7

From Proteopedia

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Current revision (11:11, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2px7' size='340' side='right'caption='[[2px7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2px7' size='340' side='right'caption='[[2px7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PX7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PX7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispD, TTHA0171 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [https://pdbe.org/2px7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [https://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2px7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [https://pdbe.org/2px7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [https://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2px7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
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[https://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Chang, S H]]
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[[Category: Chang S-H]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Chen, L Q]]
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[[Category: Chen L-Q]]
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[[Category: Ebihara, A]]
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[[Category: Ebihara A]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Lee, D]]
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[[Category: Lee D]]
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[[Category: Liu, Z J]]
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[[Category: Liu Z-J]]
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[[Category: Nguyen, D]]
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[[Category: Nguyen D]]
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[[Category: Structural genomic]]
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[[Category: Rose JP]]
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[[Category: Rose, J P]]
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[[Category: Shinkai A]]
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[[Category: Shinkai, A]]
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[[Category: Tsukuda M]]
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[[Category: Tsukuda, M]]
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[[Category: Wang B-C]]
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[[Category: Wang, B C]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
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[[Category: Ispd]]
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[[Category: Ispd_thet8]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Rsgi]]
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[[Category: Secsg]]
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[[Category: Transferase]]
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[[Category: Ttha0171]]
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Current revision

Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8

PDB ID 2px7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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