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2qy9

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Current revision (11:42, 30 August 2023) (edit) (undo)
 
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<StructureSection load='2qy9' size='340' side='right'caption='[[2qy9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2qy9' size='340' side='right'caption='[[2qy9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qy9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QY9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qy9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QY9 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ftsY ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qy9 OCA], [https://pdbe.org/2qy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qy9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qy9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qy9 OCA], [https://pdbe.org/2qy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qy9 RCSB], [https://www.ebi.ac.uk/pdbsum/2qy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qy9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FTSY_ECOLI FTSY_ECOLI]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:8194520</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15148364</ref> <ref>PMID:17682051</ref>
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[https://www.uniprot.org/uniprot/FTSY_ECOLI FTSY_ECOLI] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:8194520</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15148364</ref> <ref>PMID:17682051</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bange, G]]
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[[Category: Bange G]]
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[[Category: Parlitz, R]]
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[[Category: Parlitz R]]
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[[Category: Sinning, I]]
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[[Category: Sinning I]]
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[[Category: Wild, K]]
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[[Category: Wild K]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Ftsy]]
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[[Category: Gtp-binding]]
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[[Category: Inner membrane]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Protein targeting]]
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[[Category: Protein transport]]
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[[Category: Ribonucleoprotein]]
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[[Category: Rna-binding]]
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[[Category: Signal recognition particle]]
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[[Category: Simibi class gtpase]]
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[[Category: Srp receptor]]
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Current revision

Structure of the NG+1 construct of the E. coli SRP receptor FtsY

PDB ID 2qy9

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