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2r57
From Proteopedia
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<StructureSection load='2r57' size='340' side='right'caption='[[2r57]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2r57' size='340' side='right'caption='[[2r57]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2r57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2r57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R57 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r57 OCA], [https://pdbe.org/2r57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r57 RCSB], [https://www.ebi.ac.uk/pdbsum/2r57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r57 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r57 OCA], [https://pdbe.org/2r57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r57 RCSB], [https://www.ebi.ac.uk/pdbsum/2r57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r57 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/SCM_DROME SCM_DROME] Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.<ref>PMID:15280237</ref> [UniProtKB:Q9W3C1] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Polycomb|Polycomb]] | + | *[[Polycomb complex proteins 3D structures|Polycomb complex proteins 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Drosophila melanogaster]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Grimm | + | [[Category: Grimm C]] |
| - | [[Category: Mueller | + | [[Category: Mueller CW]] |
| - | [[Category: Steuerwald | + | [[Category: Steuerwald U]] |
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Current revision
Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM)
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