3c76
From Proteopedia
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<StructureSection load='3c76' size='340' side='right'caption='[[3c76]], [[Resolution|resolution]] 1.07Å' scene=''> | <StructureSection load='3c76' size='340' side='right'caption='[[3c76]], [[Resolution|resolution]] 1.07Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3c76]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3c76]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2asz 2asz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C76 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c76 OCA], [https://pdbe.org/3c76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c76 RCSB], [https://www.ebi.ac.uk/pdbsum/3c76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c76 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c76 OCA], [https://pdbe.org/3c76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c76 RCSB], [https://www.ebi.ac.uk/pdbsum/3c76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c76 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Rhodnius prolixus]] |
| - | [[Category: Amoia | + | [[Category: Amoia AM]] |
| - | [[Category: Montfort | + | [[Category: Montfort WR]] |
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Current revision
1.07 A crystal structure of L133V mutant of nitrophorin 4 from Rhodnius prolixus complexed with ammonia at PH 7.5
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