This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3cxm
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3cxm' size='340' side='right'caption='[[3cxm]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='3cxm' size='340' side='right'caption='[[3cxm]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cxm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3cxm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_naiffi Leishmania naiffi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene>, <scene name='pdbligand=URB:5-BROMOPYRIMIDINE-2,4(1H,3H)-DIONE'>URB</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene>, <scene name='pdbligand=URB:5-BROMOPYRIMIDINE-2,4(1H,3H)-DIONE'>URB</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxm OCA], [https://pdbe.org/3cxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxm RCSB], [https://www.ebi.ac.uk/pdbsum/3cxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxm ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxm OCA], [https://pdbe.org/3cxm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxm RCSB], [https://www.ebi.ac.uk/pdbsum/3cxm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D0VWU0_9TRYP D0VWU0_9TRYP] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.[HAMAP-Rule:MF_03166][RuleBase:RU003780] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Leishmania naiffi]] | |
| - | + | [[Category: Larson ET]] | |
| - | + | [[Category: Merritt EA]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: Leishmania]] | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
Leishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracil
| |||||||||||
