This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3dhc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:47, 30 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3dhc' size='340' side='right'caption='[[3dhc]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='3dhc' size='340' side='right'caption='[[3dhc]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3dhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bactk Bactk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHC FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3dhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis_serovar_kurstaki Bacillus thuringiensis serovar kurstaki]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DHC FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYK:N-HEXANOYL-L-HOMOCYSTEINE'>CYK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a7m|2a7m]], [[2r2d|2r2d]], [[3dha|3dha]], [[3dhb|3dhb]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYK:N-HEXANOYL-L-HOMOCYSTEINE'>CYK</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aiiA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29339 BACTK])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dhc OCA], [https://pdbe.org/3dhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dhc RCSB], [https://www.ebi.ac.uk/pdbsum/3dhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dhc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dhc OCA], [https://pdbe.org/3dhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dhc RCSB], [https://www.ebi.ac.uk/pdbsum/3dhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dhc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/AHLLA_BACTK AHLLA_BACTK]] Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.<ref>PMID:16314577</ref>
+
[https://www.uniprot.org/uniprot/AHLLA_BACTK AHLLA_BACTK] Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.<ref>PMID:16314577</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 34: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bactk]]
+
[[Category: Bacillus thuringiensis serovar kurstaki]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Fast, W]]
+
[[Category: Fast W]]
-
[[Category: Liu, D]]
+
[[Category: Liu D]]
-
[[Category: Momb, J]]
+
[[Category: Momb J]]
-
[[Category: Moulin, A]]
+
[[Category: Moulin A]]
-
[[Category: Petsko, G A]]
+
[[Category: Petsko GA]]
-
[[Category: Ringe, D]]
+
[[Category: Ringe D]]
-
[[Category: Thomas, P W]]
+
[[Category: Thomas PW]]
-
[[Category: Ahl lactonase]]
+
-
[[Category: Catalytic mechanism]]
+
-
[[Category: General acid]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: N-acyl homocysteine thiolactone]]
+
-
[[Category: Product complex]]
+
-
[[Category: Qourum quenching]]
+
-
[[Category: Zinc bimetallohydrolase]]
+

Current revision

1.3 Angstrom Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homocysteine Bound to The catalytic Metal Center

PDB ID 3dhc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3dhc"
Personal tools