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3drw

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Current revision (12:52, 30 August 2023) (edit) (undo)
 
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<StructureSection load='3drw' size='340' side='right'caption='[[3drw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3drw' size='340' side='right'caption='[[3drw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3drw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3drw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DRW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u2x|1u2x]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfkC, PH1645 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/ADP-specific_phosphofructokinase ADP-specific phosphofructokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.146 2.7.1.146] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3drw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3drw OCA], [https://pdbe.org/3drw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3drw RCSB], [https://www.ebi.ac.uk/pdbsum/3drw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3drw ProSAT], [https://www.topsan.org/Proteins/MCSG/3drw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3drw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3drw OCA], [https://pdbe.org/3drw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3drw RCSB], [https://www.ebi.ac.uk/pdbsum/3drw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3drw ProSAT], [https://www.topsan.org/Proteins/MCSG/3drw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/K6PF_PYRHO K6PF_PYRHO]] Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor (By similarity).
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[https://www.uniprot.org/uniprot/K6PF_PYRHO K6PF_PYRHO] Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pyrococcus shinkaii]]
 
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[[Category: ADP-specific phosphofructokinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Brown, G]]
 
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[[Category: Cuff, M E]]
 
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[[Category: Edwards, A M]]
 
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[[Category: Jia, Z]]
 
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[[Category: Joachimiak, A]]
 
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[[Category: Kochinyan, S]]
 
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[[Category: Structural genomic]]
 
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[[Category: Savchenko, A]]
 
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[[Category: Singer, A U]]
 
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[[Category: Skarina, T]]
 
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[[Category: Yakunin, A F]]
 
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[[Category: 6-phosphofructokinase]]
 
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[[Category: Adp]]
 
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[[Category: Amp]]
 
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[[Category: Glycolysis]]
 
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[[Category: Kinase]]
 
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[[Category: Magnesium]]
 
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[[Category: Mcsg]]
 
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[[Category: Metal-binding]]
 
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[[Category: PSI, Protein structure initiative]]
 
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Transferase]]
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[[Category: Brown G]]
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[[Category: Cuff ME]]
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[[Category: Edwards AM]]
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[[Category: Jia Z]]
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[[Category: Joachimiak A]]
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[[Category: Kochinyan S]]
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[[Category: Savchenko A]]
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[[Category: Singer AU]]
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[[Category: Skarina T]]
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[[Category: Yakunin AF]]

Current revision

Crystal Structure of a Phosphofructokinase from Pyrococcus horikoshii OT3 with AMP

PDB ID 3drw

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OCA

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