3udv

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<StructureSection load='3udv' size='340' side='right'caption='[[3udv]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='3udv' size='340' side='right'caption='[[3udv]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3udv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UDV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3udv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UDV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=J1C:5-S-[1-(2-{[(2-AMINO-7,7-DIMETHYL-4-OXO-3,4,7,8-TETRAHYDROPTERIDIN-6-YL)CARBONYL]AMINO}ETHYL)PIPERIDIN-4-YL]-5-THIOADENOSINE'>J1C</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ud5|3ud5]], [[3ude|3ude]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=J1C:5-S-[1-(2-{[(2-AMINO-7,7-DIMETHYL-4-OXO-3,4,7,8-TETRAHYDROPTERIDIN-6-YL)CARBONYL]AMINO}ETHYL)PIPERIDIN-4-YL]-5-THIOADENOSINE'>J1C</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0142, foIK, folK, JW0138 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3udv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3udv OCA], [https://pdbe.org/3udv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3udv RCSB], [https://www.ebi.ac.uk/pdbsum/3udv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3udv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3udv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3udv OCA], [https://pdbe.org/3udv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3udv RCSB], [https://www.ebi.ac.uk/pdbsum/3udv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3udv ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ji, X]]
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[[Category: Ji X]]
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[[Category: Shaw, G]]
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[[Category: Shaw G]]
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[[Category: Shi, G]]
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[[Category: Shi G]]
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[[Category: Alpha beta]]
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[[Category: Atp binding]]
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[[Category: Kinase]]
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[[Category: Pyrophosphoryl transfer]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 13:10, 30 August 2023

Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1C

PDB ID 3udv

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