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3fu7

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Current revision (06:51, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3fu7' size='340' side='right'caption='[[3fu7]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
<StructureSection load='3fu7' size='340' side='right'caption='[[3fu7]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fu7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_16460 Atcc 16460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FU7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fu7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FU7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DM:2,6-DIMETHOXYPHENOL'>3DM</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=D2M:4-(2,6-DIMETHOXYPHENOXY)-2,6-DIMETHOXYPHENOL'>D2M</scene>, <scene name='pdbligand=KIA:2,6-DIMETHOXYCYCLOHEXA-2,5-DIENE-1,4-DIONE'>KIA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OHI:3-(2-OXO-2H-IMIDAZOL-4-YL)-L-ALANINE'>OHI</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DM:2,6-DIMETHOXYPHENOL'>3DM</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=D2M:4-(2,6-DIMETHOXYPHENOXY)-2,6-DIMETHOXYPHENOL'>D2M</scene>, <scene name='pdbligand=KIA:2,6-DIMETHOXYCYCLOHEXA-2,5-DIENE-1,4-DIONE'>KIA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OHI:3-(2-OXO-2H-IMIDAZOL-4-YL)-L-ALANINE'>OHI</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2q9o|2q9o]], [[3fu8|3fu8]], [[3fu9|3fu9]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LAC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=204285 ATCC 16460])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Laccase Laccase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fu7 OCA], [https://pdbe.org/3fu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fu7 RCSB], [https://www.ebi.ac.uk/pdbsum/3fu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fu7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fu7 OCA], [https://pdbe.org/3fu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fu7 RCSB], [https://www.ebi.ac.uk/pdbsum/3fu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fu7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LAC1_MELAO LAC1_MELAO]] Lignin degradation and detoxification of lignin-derived products (Probable).<ref>PMID:15474046</ref>
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[https://www.uniprot.org/uniprot/LAC1_MELAO LAC1_MELAO] Lignin degradation and detoxification of lignin-derived products (Probable).<ref>PMID:15474046</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 16460]]
 
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[[Category: Laccase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hakulinen, N]]
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[[Category: Melanocarpus albomyces]]
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[[Category: Kallio, J P]]
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[[Category: Hakulinen N]]
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[[Category: Rouvinen, J]]
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[[Category: Kallio JP]]
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[[Category: 6-dimethoxyphenol]]
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[[Category: Rouvinen J]]
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[[Category: Complex structure]]
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[[Category: Glycoprotein]]
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[[Category: Lignin degradation]]
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[[Category: Metal-binding]]
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[[Category: Multicopper oxidase]]
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[[Category: Oxidation of phenolic compound]]
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[[Category: Oxidoreductase]]
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Current revision

Melanocarpus albomyces laccase crystal soaked (4 sec) with 2,6-dimethoxyphenol

PDB ID 3fu7

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