1mom
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1mom.jpg|left|200px]] | [[Image:1mom.jpg|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1mom", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | + | or leave the SCENE parameter empty for the default display. | |
| - | | | + | --> |
| - | | | + | {{STRUCTURE_1mom| PDB=1mom | SCENE= }} |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA''' | '''CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA''' | ||
| Line 19: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1MOM is a [[Single protein]] structure | + | 1MOM is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOM OCA]. |
==Reference== | ==Reference== | ||
Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of Momordica charantia., Husain J, Tickle IJ, Wood SP, FEBS Lett. 1994 Apr 4;342(2):154-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8143869 8143869] | Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of Momordica charantia., Husain J, Tickle IJ, Wood SP, FEBS Lett. 1994 Apr 4;342(2):154-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8143869 8143869] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: | + | [[Category: RRNA N-glycosylase]] |
[[Category: Husain, J.]] | [[Category: Husain, J.]] | ||
[[Category: Tickle, I J.]] | [[Category: Tickle, I J.]] | ||
[[Category: Wood, S P.]] | [[Category: Wood, S P.]] | ||
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:31:43 2008'' | |
| - | + | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 22:31, 2 May 2008
CRYSTAL STRUCTURE OF MOMORDIN, A TYPE I RIBOSOME INACTIVATING PROTEIN FROM THE SEEDS OF MOMORDICA CHARANTIA
Overview
A type I ribosome-inactivating protein, extracted and purified from M. charantia seeds, was crystallised by vapour diffusion with polyethylene glycol at pH 7.2. X-ray data were collected to 2.1 A resolution and the structure solved by molecular replacement using the A-chain coordinates of ricin. The overall fold of the protein is similar to ricin but there are differences in secondary structure, on the surface and in the active site cleft. These differences are probably due in part to the evolution of the protein without a B-chain partner. The most extensive reorganisation occurs at the C-terminus whereas Tyr70 shows the greatest change in the active site cleft.
About this Structure
1MOM is a Single protein structure. Full crystallographic information is available from OCA.
Reference
Crystal structure of momordin, a type I ribosome inactivating protein from the seeds of Momordica charantia., Husain J, Tickle IJ, Wood SP, FEBS Lett. 1994 Apr 4;342(2):154-8. PMID:8143869 Page seeded by OCA on Sat May 3 01:31:43 2008
