3i8t

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Current revision (07:40, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3i8t' size='340' side='right'caption='[[3i8t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3i8t' size='340' side='right'caption='[[3i8t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3i8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I8T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3i8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I8T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gal-4, Lgals4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i8t OCA], [https://pdbe.org/3i8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i8t RCSB], [https://www.ebi.ac.uk/pdbsum/3i8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i8t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i8t OCA], [https://pdbe.org/3i8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i8t RCSB], [https://www.ebi.ac.uk/pdbsum/3i8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i8t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LEG4_MOUSE LEG4_MOUSE]] Galectin that binds lactose and a related range of sugars (By similarity).
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[https://www.uniprot.org/uniprot/LEG4_MOUSE LEG4_MOUSE] Galectin that binds lactose and a related range of sugars (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Brynda, J]]
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[[Category: Brynda J]]
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[[Category: Krejcirikova, V]]
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[[Category: Krejcirikova V]]
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[[Category: Rezacova, P]]
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[[Category: Rezacova P]]
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[[Category: Carbohydrate binding]]
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[[Category: Lectin]]
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[[Category: Molecular recognition]]
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[[Category: S-type lectin]]
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[[Category: Sugar binding protein]]
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Current revision

N-terminal CRD1 domain of mouse Galectin-4 in complex with lactose

PDB ID 3i8t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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