3ife

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Current revision (07:45, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3ife' size='340' side='right'caption='[[3ife]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='3ife' size='340' side='right'caption='[[3ife]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ife]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_ames_"ancestor" Bacillus anthracis ames "ancestor"]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ife]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._'Ames_Ancestor' Bacillus anthracis str. 'Ames Ancestor']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IFE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3588, BA_3872, GBAA_3872, pepT, pepT-1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261594 Bacillus anthracis Ames "Ancestor"])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tripeptide_aminopeptidase Tripeptide aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.4 3.4.11.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ife OCA], [https://pdbe.org/3ife PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ife RCSB], [https://www.ebi.ac.uk/pdbsum/3ife PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ife ProSAT], [https://www.topsan.org/Proteins/CSGID/3ife TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ife OCA], [https://pdbe.org/3ife PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ife RCSB], [https://www.ebi.ac.uk/pdbsum/3ife PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ife ProSAT], [https://www.topsan.org/Proteins/CSGID/3ife TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PEPT_BACAN PEPT_BACAN]] Cleaves the N-terminal amino acid of tripeptides (By similarity).
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[https://www.uniprot.org/uniprot/PEPT_BACAN PEPT_BACAN] Cleaves the N-terminal amino acid of tripeptides (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus anthracis ames ancestor]]
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[[Category: Bacillus anthracis str. 'Ames Ancestor']]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tripeptide aminopeptidase]]
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[[Category: Anderson WF]]
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[[Category: Anderson, W F]]
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[[Category: Dubrovska I]]
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[[Category: Structural genomic]]
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[[Category: Halavaty A]]
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[[Category: Dubrovska, I]]
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[[Category: Minasov G]]
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[[Category: Halavaty, A]]
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[[Category: Shuvalova L]]
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[[Category: Minasov, G]]
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[[Category: Winsor J]]
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[[Category: Shuvalova, L]]
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[[Category: Winsor, J]]
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[[Category: Aminopeptidase]]
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[[Category: Csgid]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Metallopeptidase]]
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[[Category: Metalloprotease]]
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[[Category: Pept-1]]
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[[Category: Peptidase t]]
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[[Category: Protease]]
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Current revision

1.55 Angstrom Resolution Crystal Structure of Peptidase T (pepT-1) from Bacillus anthracis str. 'Ames Ancestor'.

PDB ID 3ife

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