3il4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='3il4' size='340' side='right'caption='[[3il4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3il4' size='340' side='right'caption='[[3il4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3il4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IL4 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3il4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IL4 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3il3|3il3]], [[3il5|3il5]], [[3il6|3il6]], [[3il7|3il7]], [[3il9|3il9]]</div></td></tr>
+
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EF_2885, fabH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 "Enterococcus proteiformis" Thiercelin and Jouhaud 1903])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_III Beta-ketoacyl-[acyl-carrier-protein] synthase III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.180 2.3.1.180] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3il4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3il4 OCA], [https://pdbe.org/3il4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3il4 RCSB], [https://www.ebi.ac.uk/pdbsum/3il4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3il4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3il4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3il4 OCA], [https://pdbe.org/3il4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3il4 RCSB], [https://www.ebi.ac.uk/pdbsum/3il4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3il4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/FABH_ENTFA FABH_ENTFA]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).
+
[https://www.uniprot.org/uniprot/FABH_ENTFA FABH_ENTFA] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 39: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
+
[[Category: Enterococcus faecalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Appelt, K]]
+
[[Category: Appelt K]]
-
[[Category: Cortez, J]]
+
[[Category: Cortez J]]
-
[[Category: Gajiwala, K S]]
+
[[Category: Gajiwala KS]]
-
[[Category: Lu, J]]
+
[[Category: Lu J]]
-
[[Category: Margosiak, S]]
+
[[Category: Margosiak S]]
-
[[Category: Nie, Z]]
+
[[Category: Nie Z]]
-
[[Category: Su, Y]]
+
[[Category: Su Y]]
-
[[Category: Acyltransferase]]
+
-
[[Category: Antibiotic]]
+
-
[[Category: Cytoplasm]]
+
-
[[Category: Fabh]]
+
-
[[Category: Fatty acid biosynthesis]]
+
-
[[Category: Lipid synthesis]]
+
-
[[Category: Multifunctional enzyme]]
+
-
[[Category: Transferase]]
+

Revision as of 07:52, 6 September 2023

Structure of E. faecalis FabH in complex with acetyl CoA

PDB ID 3il4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3il4"
Personal tools