3jyp

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Current revision (08:06, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3jyp' size='340' side='right'caption='[[3jyp]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
<StructureSection load='3jyp' size='340' side='right'caption='[[3jyp]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corgl Corgl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2nlo|2nlo]], [[3jyo|3jyo]], [[3jyq|3jyq]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 CORGL])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [https://pdbe.org/3jyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [https://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [https://pdbe.org/3jyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [https://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>
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[https://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Corgl]]
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[[Category: Corynebacterium glutamicum ATCC 13032]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hoeppner, A]]
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[[Category: Hoeppner A]]
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[[Category: Niefind, K]]
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[[Category: Niefind K]]
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[[Category: Schomburg, D]]
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[[Category: Schomburg D]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Nad]]
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[[Category: Nadh]]
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[[Category: Oxidoreductase]]
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[[Category: Quinate]]
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[[Category: Quinate dehyrogenase]]
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[[Category: Ternary complex]]
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Current revision

Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH

PDB ID 3jyp

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OCA

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