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3ki8
From Proteopedia
(Difference between revisions)
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<StructureSection load='3ki8' size='340' side='right'caption='[[3ki8]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='3ki8' size='340' side='right'caption='[[3ki8]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ki8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3ki8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KI8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ki8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ki8 OCA], [https://pdbe.org/3ki8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ki8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ki8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ki8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ki8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ki8 OCA], [https://pdbe.org/3ki8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ki8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ki8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ki8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NITR_PYRAB NITR_PYRAB] Nitrilase that hydrolyzes preferentially aliphatic nitriles like malononitrile and fumaronitrile in vitro. These dinitriles are converted to the corresponding monoacid mononitriles, showing the enzyme is regioselective. Cannot hydrolyze compounds with a nitrile group bound to an aromatic ring or amino acid. Its biological role is unknown.<ref>PMID:16495079</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Beta-ureidopropionase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pyrococcus abyssi GE5]] |
| - | [[Category: Antranikian | + | [[Category: Antranikian G]] |
| - | [[Category: Raczynska | + | [[Category: Raczynska J]] |
| - | [[Category: Rypniewski | + | [[Category: Rypniewski W]] |
| - | [[Category: Vorgias | + | [[Category: Vorgias C]] |
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Current revision
Crystal structure of hyperthermophilic nitrilase
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