This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3knu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:19, 6 September 2023) (edit) (undo)
 
Line 1: Line 1:
==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum==
==Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum==
-
<StructureSection load='3knu' size='340' side='right' caption='[[3knu]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+
<StructureSection load='3knu' size='340' side='right'caption='[[3knu]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Anapz Anapz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KNU FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3knu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KNU FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e5y|3e5y]], [[3ief|3ief]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, APH_1267 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=212042 ANAPZ])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knu OCA], [https://pdbe.org/3knu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3knu RCSB], [https://www.ebi.ac.uk/pdbsum/3knu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3knu ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.221 and 2.1.1.228 2.1.1.221 and 2.1.1.228] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knu OCA], [http://pdbe.org/3knu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3knu RCSB], [http://www.ebi.ac.uk/pdbsum/3knu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3knu ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ]] Specifically methylates guanosine-37 in various tRNAs (By similarity).
+
[https://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ] Specifically methylates guanosine-37 in various tRNAs (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kn/3knu_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 21: Line 19:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3knu ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3knu ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
 +
 +
==See Also==
 +
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Anapz]]
+
[[Category: Anaplasma phagocytophilum str. HZ]]
-
[[Category: Transferase]]
+
[[Category: Large Structures]]
-
[[Category: Structural genomic]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Niaid]]
+
-
[[Category: Protein knot]]
+
-
[[Category: Rna-binding protein]]
+
-
[[Category: S-adenosyl-l-methionine]]
+
-
[[Category: Ssgcid]]
+
-
[[Category: Trefoil knot]]
+
-
[[Category: Trna methyl transferase]]
+
-
[[Category: Trna processing]]
+

Current revision

Crystal structure of tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum

PDB ID 3knu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools