3l9k

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Current revision (08:33, 6 September 2023) (edit) (undo)
 
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==Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure==
==Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure==
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<StructureSection load='3l9k' size='340' side='right' caption='[[3l9k]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3l9k' size='340' side='right'caption='[[3l9k]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3l9k]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L9K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3l9k]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L9K FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l7h|3l7h]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">robl, CG10751, Dmel_CG10751 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME]), sw, Cdic, Dic19B, CG18000 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l9k OCA], [https://pdbe.org/3l9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l9k RCSB], [https://www.ebi.ac.uk/pdbsum/3l9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l9k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l9k OCA], [http://pdbe.org/3l9k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l9k RCSB], [http://www.ebi.ac.uk/pdbsum/3l9k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l9k ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DYIN_DROME DYIN_DROME]] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).<ref>PMID:11071907</ref>
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[https://www.uniprot.org/uniprot/Q7KMS3_DROME Q7KMS3_DROME]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Dynein|Dynein]]
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*[[Dynein 3D structures|Dynein 3D structures]]
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
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[[Category: Barbar, E]]
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[[Category: Large Structures]]
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[[Category: Hall, J]]
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[[Category: Barbar E]]
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[[Category: Karplus, P A]]
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[[Category: Hall J]]
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[[Category: Dynein]]
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[[Category: Karplus PA]]
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[[Category: Hydrolase]]
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[[Category: Ic]]
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[[Category: Intermediate chain]]
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[[Category: Km23]]
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[[Category: Lc7]]
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[[Category: Light chain 7]]
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[[Category: Lysosome]]
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[[Category: Membrane]]
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[[Category: Microtubule]]
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[[Category: Motor protein]]
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[[Category: Nucleus]]
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[[Category: Roadblock]]
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[[Category: Wd repeat]]
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Current revision

Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure

PDB ID 3l9k

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