3lix

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Current revision (08:37, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3lix' size='340' side='right'caption='[[3lix]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3lix' size='340' side='right'caption='[[3lix]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Htlv-1 Htlv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LIX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_T-cell_leukemia_virus_type_I Human T-cell leukemia virus type I]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LIX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E17:N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide'>E17</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2b7f|2b7f]], [[3liq|3liq]], [[3lin|3lin]], [[3lit|3lit]], [[3liv|3liv]], [[3liy|3liy]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E17:N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide'>E17</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prt ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11908 HTLV-1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lix OCA], [https://pdbe.org/3lix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lix RCSB], [https://www.ebi.ac.uk/pdbsum/3lix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lix ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lix OCA], [https://pdbe.org/3lix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lix RCSB], [https://www.ebi.ac.uk/pdbsum/3lix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lix ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q82134_9DELA Q82134_9DELA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Htlv-1]]
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[[Category: Human T-cell leukemia virus type I]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gustchina, A]]
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[[Category: Gustchina A]]
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[[Category: Kiso, Y]]
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[[Category: Kiso Y]]
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[[Category: Li, M]]
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[[Category: Li M]]
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[[Category: Nguyen, J]]
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[[Category: Nguyen J]]
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[[Category: Satoh, T]]
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[[Category: Satoh T]]
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[[Category: Wlodawer, A]]
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[[Category: Wlodawer A]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

crystal structure of htlv protease complexed with the inhibitor KNI-10729

PDB ID 3lix

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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