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3lnc

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Current revision (08:41, 6 September 2023) (edit) (undo)
 
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==Crystal structure of guanylate kinase from Anaplasma phagocytophilum==
==Crystal structure of guanylate kinase from Anaplasma phagocytophilum==
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<StructureSection load='3lnc' size='340' side='right' caption='[[3lnc]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3lnc' size='340' side='right'caption='[[3lnc]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lnc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Anapz Anapz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LNC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lnc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LNC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gmk, APH_0170 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=212042 ANAPZ])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lnc OCA], [https://pdbe.org/3lnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lnc RCSB], [https://www.ebi.ac.uk/pdbsum/3lnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lnc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lnc OCA], [http://pdbe.org/3lnc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lnc RCSB], [http://www.ebi.ac.uk/pdbsum/3lnc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lnc ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KGUA_ANAPZ KGUA_ANAPZ]] Essential for recycling GMP and indirectly, cGMP (By similarity).
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[https://www.uniprot.org/uniprot/KGUA_ANAPZ KGUA_ANAPZ] Essential for recycling GMP and indirectly, cGMP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/3lnc_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/3lnc_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lnc ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lnc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anapz]]
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[[Category: Anaplasma phagocytophilum str. HZ]]
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[[Category: Guanylate kinase]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Als collaborative crystallography]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Emerald biostructure]]
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[[Category: Kinase]]
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[[Category: Nucleotide-binding]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Current revision

Crystal structure of guanylate kinase from Anaplasma phagocytophilum

PDB ID 3lnc

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