3m6g

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<StructureSection load='3m6g' size='340' side='right'caption='[[3m6g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3m6g' size='340' side='right'caption='[[3m6g]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3m6g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lobophora_variegata Lobophora variegata] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M6G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3m6g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M6G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LO3:(1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-HYDROXY-9-{(1S,2S,3S)-2-HYDROXY-5-[(2S,4R,6S)-4-METHOXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]-1,3-DIMETHYLPENTYL}-3,5,7,17-TETRAMETHOXY-8,14-DIMETHYL-11H-SPIRO[10,23-DIOXABICYCLO[17.3.1]TRICOSA-12,14,20-TRIENE-4,2-OXIRAN]-11-ONE'>LO3</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yxq|1yxq]], [[2vyp|2vyp]], [[2asm|2asm]], [[2aso|2aso]], [[2asp|2asp]], [[1qz5|1qz5]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LO3:(1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-HYDROXY-9-{(1S,2S,3S)-2-HYDROXY-5-[(2S,4R,6S)-4-METHOXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]-1,3-DIMETHYLPENTYL}-3,5,7,17-TETRAMETHOXY-8,14-DIMETHYL-11H-SPIRO[10,23-DIOXABICYCLO[17.3.1]TRICOSA-12,14,20-TRIENE-4,2-OXIRAN]-11-ONE'>LO3</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m6g OCA], [https://pdbe.org/3m6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m6g RCSB], [https://www.ebi.ac.uk/pdbsum/3m6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m6g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m6g OCA], [https://pdbe.org/3m6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m6g RCSB], [https://www.ebi.ac.uk/pdbsum/3m6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m6g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lobophora variegata]]
 
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Allingham, J S]]
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[[Category: Allingham JS]]
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[[Category: Actin]]
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[[Category: Actin dimer]]
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[[Category: Atp-binding]]
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[[Category: Cytoskeleton]]
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[[Category: Lobophorolide]]
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[[Category: Macrolide]]
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[[Category: Marine toxin]]
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[[Category: Muscle protein]]
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[[Category: Nucleotide-binding]]
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[[Category: Structural protein]]
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Revision as of 08:49, 6 September 2023

Crystal structure of actin in complex with lobophorolide

PDB ID 3m6g

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