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3mjs

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Current revision (08:54, 6 September 2023) (edit) (undo)
 
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==Structure of A-type Ketoreductases from Modular Polyketide Synthase==
==Structure of A-type Ketoreductases from Modular Polyketide Synthase==
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<StructureSection load='3mjs' size='340' side='right' caption='[[3mjs]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='3mjs' size='340' side='right'caption='[[3mjs]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mjs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1459 As 4.1459]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MJS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mjs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_nodosus Streptomyces nodosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MJS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mjc|3mjc]], [[3mje|3mje]], [[3mjt|3mjt]], [[3mjv|3mjv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amphB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=40318 AS 4.1459])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mjs OCA], [https://pdbe.org/3mjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mjs RCSB], [https://www.ebi.ac.uk/pdbsum/3mjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mjs ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mjs OCA], [http://pdbe.org/3mjs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mjs RCSB], [http://www.ebi.ac.uk/pdbsum/3mjs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mjs ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q93NW7_9ACTN Q93NW7_9ACTN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: As 4 1459]]
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[[Category: Large Structures]]
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[[Category: Keatinge-Clay, A T]]
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[[Category: Streptomyces nodosus]]
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[[Category: Piasecki, S K]]
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[[Category: Keatinge-Clay AT]]
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[[Category: Taylor, C A]]
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[[Category: Piasecki SK]]
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[[Category: Zheng, J]]
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[[Category: Taylor CA]]
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[[Category: Oxidoreductase]]
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[[Category: Zheng J]]
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[[Category: Rossmann fold]]
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Current revision

Structure of A-type Ketoreductases from Modular Polyketide Synthase

PDB ID 3mjs

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