3mpd

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Current revision (08:58, 6 September 2023) (edit) (undo)
 
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==Crystal structure of nucleoside diphosphate kinase from encephalitozoon cuniculi, cubic form, apo==
==Crystal structure of nucleoside diphosphate kinase from encephalitozoon cuniculi, cubic form, apo==
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<StructureSection load='3mpd' size='340' side='right' caption='[[3mpd]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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<StructureSection load='3mpd' size='340' side='right'caption='[[3mpd]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mpd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enccn Enccn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MPD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mpd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MPD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECU06_1530, HM-1:IMSS, NDK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6035 ENCCN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpd OCA], [https://pdbe.org/3mpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mpd RCSB], [https://www.ebi.ac.uk/pdbsum/3mpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mpd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mpd OCA], [http://pdbe.org/3mpd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mpd RCSB], [http://www.ebi.ac.uk/pdbsum/3mpd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mpd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NDK_ENCCU NDK_ENCCU]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
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[https://www.uniprot.org/uniprot/NDK_ENCCU NDK_ENCCU] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enccn]]
 
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[[Category: Nucleoside-diphosphate kinase]]
 
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[[Category: Structural genomic]]
 
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[[Category: Emerald biostructure]]
 
[[Category: Encephalitozoon cuniculi]]
[[Category: Encephalitozoon cuniculi]]
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[[Category: Kinase]]
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[[Category: Large Structures]]
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[[Category: Niaid]]
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[[Category: Nih]]
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[[Category: Sbri]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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[[Category: Uw]]
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Current revision

Crystal structure of nucleoside diphosphate kinase from encephalitozoon cuniculi, cubic form, apo

PDB ID 3mpd

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