3n0t
From Proteopedia
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==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A== | ==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A== | ||
| - | <StructureSection load='3n0t' size='340' side='right' caption='[[3n0t]], [[Resolution|resolution]] 2.45Å' scene=''> | + | <StructureSection load='3n0t' size='340' side='right'caption='[[3n0t]], [[Resolution|resolution]] 2.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N0T FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OPY:(3S)-4-OXO-4-PIPERIDIN-1-YLBUTANE-1,3-DIAMINE'>OPY</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0t OCA], [https://pdbe.org/3n0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n0t RCSB], [https://www.ebi.ac.uk/pdbsum/3n0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n0t ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DPP2_HUMAN DPP2_HUMAN] Plays an important role in the degradation of some oligopeptides.<ref>PMID:15487984</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n0t ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n0t ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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| + | ==See Also== | ||
| + | *[[Dipeptidyl peptidase 3D structures|Dipeptidyl peptidase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Bochkarev A]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Cossar | + | [[Category: Cossar D]] |
| - | [[Category: Crombet | + | [[Category: Crombet L]] |
| - | [[Category: Dobrovetsky | + | [[Category: Dobrovetsky E]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Haffner | + | [[Category: Haffner C]] |
| - | [[Category: Hassell | + | [[Category: Hassell A]] |
| - | [[Category: Khutoreskaya | + | [[Category: Khutoreskaya G]] |
| - | [[Category: Pagannon | + | [[Category: Pagannon S]] |
| - | + | [[Category: Seitova A]] | |
| - | [[Category: Seitova | + | [[Category: Shewchuk L]] |
| - | [[Category: Shewchuk | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | |
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Revision as of 09:06, 6 September 2023
Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Cossar D | Crombet L | Dobrovetsky E | Edwards AM | Haffner C | Hassell A | Khutoreskaya G | Pagannon S | Seitova A | Shewchuk L | Weigelt J
