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3n3f

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Current revision (09:08, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3n3f' size='340' side='right'caption='[[3n3f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3n3f' size='340' side='right'caption='[[3n3f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3n3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3n3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3F FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COL15A1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.005&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3f OCA], [https://pdbe.org/3n3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3f RCSB], [https://www.ebi.ac.uk/pdbsum/3n3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3f OCA], [https://pdbe.org/3n3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3f RCSB], [https://www.ebi.ac.uk/pdbsum/3n3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/COFA1_HUMAN COFA1_HUMAN]] Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.<ref>PMID:10049780</ref> Restin potently inhibits angiogenesis.
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[https://www.uniprot.org/uniprot/COFA1_HUMAN COFA1_HUMAN] Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.<ref>PMID:10049780</ref> Restin potently inhibits angiogenesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Wirz, J A]]
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[[Category: Wirz JA]]
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[[Category: Association]]
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[[Category: Basement membrane]]
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[[Category: Chain selection]]
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[[Category: Collagen]]
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[[Category: Collagen xv]]
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[[Category: Collagen xviii]]
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[[Category: Extracellular matrix]]
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[[Category: Folding]]
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[[Category: Multiplexin]]
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[[Category: Protein binding]]
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[[Category: Trimerization domain]]
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[[Category: Triple helix]]
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Current revision

Crystal Structure of the Human Collagen XV Trimerization Domain: A Potent Trimerizing Unit Common to Multiplexin Collagens

PDB ID 3n3f

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OCA

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