3no9

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Current revision (09:18, 6 September 2023) (edit) (undo)
 
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==Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis==
==Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis==
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<StructureSection load='3no9' size='340' side='right' caption='[[3no9]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
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<StructureSection load='3no9' size='340' side='right'caption='[[3no9]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3no9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NO9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3no9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NO9 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fum, fumC, MT1130, MTV017.51c, Rv1098c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3no9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no9 OCA], [https://pdbe.org/3no9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3no9 RCSB], [https://www.ebi.ac.uk/pdbsum/3no9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3no9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3no9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3no9 OCA], [http://pdbe.org/3no9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3no9 RCSB], [http://www.ebi.ac.uk/pdbsum/3no9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3no9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FUMC_MYCTU FUMC_MYCTU]] Catalyzes the reversible addition of water to fumarate to give L-malate.
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[https://www.uniprot.org/uniprot/FUMC_MYCTU FUMC_MYCTU] Catalyzes the reversible addition of water to fumarate to give L-malate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fumarate hydratase]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Hung, L W]]
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[[Category: Hung L-W]]
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[[Category: Li, H]]
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[[Category: Li H]]
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[[Category: Sacchettini, J C]]
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[[Category: Sacchettini JC]]
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[[Category: Swanson, S]]
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[[Category: Swanson S]]
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[[Category: Structural genomic]]
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[[Category: Yu M]]
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[[Category: Yu, M]]
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[[Category: Apo]]
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[[Category: Lyase]]
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[[Category: Lyase class i]]
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[[Category: Tbsgc]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis

PDB ID 3no9

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