3p0l

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Current revision (09:47, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
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[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Berg, S Van Den]]
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[[Category: Berglund H]]
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[[Category: Berglund, H]]
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[[Category: Busam RD]]
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[[Category: Busam, R D]]
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[[Category: Collins R]]
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[[Category: Collins, R]]
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[[Category: Dahlgren LG]]
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[[Category: Dahlgren, L G]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Flodin S]]
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[[Category: Flodin, S]]
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[[Category: Flores A]]
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[[Category: Flores, A]]
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[[Category: Graslund S]]
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[[Category: Graslund, S]]
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[[Category: Hallberg BM]]
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[[Category: Hallberg, B M]]
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[[Category: Hammarstrom M]]
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[[Category: Hammarstrom, M]]
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[[Category: Herman MD]]
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[[Category: Herman, M D]]
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[[Category: Johansson A]]
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[[Category: Johansson, A]]
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[[Category: Johansson I]]
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[[Category: Johansson, I]]
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[[Category: Kallas A]]
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[[Category: Kallas, A]]
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[[Category: Karlberg T]]
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[[Category: Karlberg, T]]
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[[Category: Kotenyova T]]
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[[Category: Kotenyova, T]]
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[[Category: Lehtio L]]
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[[Category: Lehtio, L]]
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[[Category: Moche M]]
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[[Category: Moche, M]]
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[[Category: Nilsson ME]]
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[[Category: Nilsson, M E]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P]]
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[[Category: Nyman T]]
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[[Category: Nyman, T]]
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[[Category: Persson C]]
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[[Category: Persson, C]]
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[[Category: Sagemark J]]
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[[Category: Structural genomic]]
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[[Category: Schuler H]]
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[[Category: Sagemark, J]]
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[[Category: Siponen M]]
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[[Category: Schuler, H]]
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[[Category: Sundstrom M]]
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[[Category: Siponen, M]]
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[[Category: Svensson L]]
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[[Category: Sundstrom, M]]
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[[Category: Thorsell AG]]
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[[Category: Svensson, L]]
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[[Category: Tresaugues L]]
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[[Category: Thorsell, A G]]
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[[Category: Van Den Berg S]]
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[[Category: Tresaugues, L]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Welin M]]
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[[Category: Welin, M]]
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[[Category: Cholesterol]]
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[[Category: Cholesterol transport]]
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[[Category: Mitochondria]]
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[[Category: Sgc]]
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[[Category: Start domain]]
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[[Category: Transport protein]]
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Current revision

Human steroidogenic acute regulatory protein

PDB ID 3p0l

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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