3p7n

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Current revision (09:49, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3p7n' size='340' side='right'caption='[[3p7n]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3p7n' size='340' side='right'caption='[[3p7n]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3p7n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Erylh Erylh]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P7N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3p7n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Erythrobacter_litoralis_HTCC2594 Erythrobacter litoralis HTCC2594]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P7N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ELI_04755 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=314225 ERYLH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p7n OCA], [https://pdbe.org/3p7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p7n RCSB], [https://www.ebi.ac.uk/pdbsum/3p7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p7n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p7n OCA], [https://pdbe.org/3p7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p7n RCSB], [https://www.ebi.ac.uk/pdbsum/3p7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p7n ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LVHTH_ERYLH LVHTH_ERYLH] Has reversible, light-dependent DNA-binding activity. Upon illumination an internal FMN-protein adduct is formed which changes the protein conformation so that the previously sequestered DNA-binding domain is free to bind DNA. Binds to sequences within in its own promoter when illuminated but not when it has been incubated in the dark.<ref>PMID:21606338</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Erylh]]
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[[Category: Erythrobacter litoralis HTCC2594]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Phototropin]]
[[Category: Phototropin]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Luecke, H]]
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[[Category: Luecke H]]
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[[Category: McNulty, R]]
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[[Category: McNulty R]]
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[[Category: Dna binding protein]]
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[[Category: Light-activated transcription factor]]
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[[Category: Lov domain]]
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Current revision

Crystal structure of light activated transcription factor El222 from Erythrobacter litoralis

PDB ID 3p7n

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