3pg4

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Current revision (09:54, 6 September 2023) (edit) (undo)
 
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<StructureSection load='3pg4' size='340' side='right'caption='[[3pg4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3pg4' size='340' side='right'caption='[[3pg4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PG4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PG4 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla NDM-1, blaNDM-1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pg4 OCA], [https://pdbe.org/3pg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pg4 RCSB], [https://www.ebi.ac.uk/pdbsum/3pg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pg4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pg4 OCA], [https://pdbe.org/3pg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pg4 RCSB], [https://www.ebi.ac.uk/pdbsum/3pg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pg4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
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[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chang, H J]]
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[[Category: Chang HJ]]
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[[Category: Cho, Y S]]
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[[Category: Cho YS]]
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[[Category: Kim, H T]]
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[[Category: Kim HT]]
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[[Category: Hydrolase]]
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Current revision

The crystal structure of New Delhi Metallo-beta lactamase (NDM-1)

PDB ID 3pg4

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