3phn
From Proteopedia
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<StructureSection load='3phn' size='340' side='right'caption='[[3phn]], [[Resolution|resolution]] 1.46Å' scene=''> | <StructureSection load='3phn' size='340' side='right'caption='[[3phn]], [[Resolution|resolution]] 1.46Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3phn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3phn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_pipiens Lithobates pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHN FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.46Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phn OCA], [https://pdbe.org/3phn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phn RCSB], [https://www.ebi.ac.uk/pdbsum/3phn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phn OCA], [https://pdbe.org/3phn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phn RCSB], [https://www.ebi.ac.uk/pdbsum/3phn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/RNP30_LITPI RNP30_LITPI] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Lithobates pipiens]] |
| - | [[Category: Kurpiewska | + | [[Category: Kurpiewska K]] |
| - | [[Category: Lewinski | + | [[Category: Lewinski K]] |
| - | [[Category: Loch | + | [[Category: Loch J]] |
| - | [[Category: Ribo | + | [[Category: Ribo M]] |
| - | [[Category: Torrent | + | [[Category: Torrent G]] |
| - | [[Category: Vilanova | + | [[Category: Vilanova M]] |
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Current revision
Crystal structure of wild-type onconase with resolution 1.46 A
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