5j6p
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe== | ==Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe== | ||
| - | <StructureSection load='5j6p' size='340' side='right' caption='[[5j6p]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='5j6p' size='340' side='right'caption='[[5j6p]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5j6p]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5j6p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J6P FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j6p OCA], [https://pdbe.org/5j6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j6p RCSB], [https://www.ebi.ac.uk/pdbsum/5j6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j6p ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MIS18_SCHPO MIS18_SCHPO] Required for correct chromosome segregation where it has a role in the formation and/or maintenance of specialized chromatin at the centromere. Has a role in kinetochore assembly and CENP-A loading. Maintains the deacetylated state of histones specifically in the central core of the centromeres.<ref>PMID:15369671</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Shao | + | [[Category: Schizosaccharomyces pombe 972h-]] |
| - | [[Category: Wang | + | [[Category: Shao C]] |
| - | [[Category: Zang | + | [[Category: Wang C]] |
| - | [[Category: Zhang | + | [[Category: Zang J]] |
| - | [[Category: Zhang | + | [[Category: Zhang M]] |
| - | + | [[Category: Zhang X]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Mis18(17-118) from Schizosaccharomyces pombe
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