Protein Hfq
From Proteopedia
(Difference between revisions)
| Line 12: | Line 12: | ||
The biological assembly of Protein Hfq from ''E. coli'' is <scene name='87/875687/Cv/2'>homohexamer</scene> (PDB code [[4ht9]]). The 3D structure of the complex between Hfq and <scene name='87/875687/Cv/5'>poly(A) RNA and poly(U) RNA</scene> shows the poly(A) binding at the distal face of Hfq and poly(U) binding at its proximal face. For the poly(A) A-R-N binding site the A site shows <scene name='87/875687/Cv/4'>hydrogen bonding to Gln and Lys</scene>. The <scene name='87/875687/Cv/6'>R site shows stacking interactions as well as hydrogen bonding</scene>. The N site does not show any interaction. <scene name='87/875687/Cv/7'>The poly(U) binding site of Hfq is a classical uridine binding pocket with both stacking and hydrogen bonding interactions</scene><ref>PMID:23605038</ref>. | The biological assembly of Protein Hfq from ''E. coli'' is <scene name='87/875687/Cv/2'>homohexamer</scene> (PDB code [[4ht9]]). The 3D structure of the complex between Hfq and <scene name='87/875687/Cv/5'>poly(A) RNA and poly(U) RNA</scene> shows the poly(A) binding at the distal face of Hfq and poly(U) binding at its proximal face. For the poly(A) A-R-N binding site the A site shows <scene name='87/875687/Cv/4'>hydrogen bonding to Gln and Lys</scene>. The <scene name='87/875687/Cv/6'>R site shows stacking interactions as well as hydrogen bonding</scene>. The N site does not show any interaction. <scene name='87/875687/Cv/7'>The poly(U) binding site of Hfq is a classical uridine binding pocket with both stacking and hydrogen bonding interactions</scene><ref>PMID:23605038</ref>. | ||
| - | |||
| - | </StructureSection> | ||
== 3D Structures of protein Hfq == | == 3D Structures of protein Hfq == | ||
[[Protein Hfq 3D structures]] | [[Protein Hfq 3D structures]] | ||
| - | |||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | |||
| - | *Protein Hfq | ||
| - | |||
| - | **[[1hk9]], [[2y90]], [[2yht]], [[3qhs]], [[4rcb]], [[4rcc]], [[6bdg]] – EcHfq – ''Escherichia coli'' <br /> | ||
| - | **[[4jli]], [[4jri]], [[4jrk]], [[4juv]] – EcHfq (mutant)<br /> | ||
| - | **[[1u1s]], [[1u1t]], [[4j6y]], [[6xyj]] – PaHfq – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[3inz]], [[3m4g]], [[4mml]], [[4mmk]], [[5i21]] – PaHfq (mutant)<br /> | ||
| - | **[[2ylb]] – StHfq – ''Salmonella typhimurium''<br /> | ||
| - | **[[6gwk]] – Hfq – ''Caulobacter crescentus''<br /> | ||
| - | **[[4nl2]] – LmHfq – ''Listeria monocytogenes''<br /> | ||
| - | **[[4noy]] – LmHfq (mutant)<br /> | ||
| - | **[[5szd]] – AaHfq – ''Aquifex aeolicus''<br /> | ||
| - | **[[3sb2]] – Hfq - ''Herbaspirillum seropedicae''<br /> | ||
| - | **[[1kq1]] – SaHfq – ''Staphylococcus aureus''<br /> | ||
| - | **[[2qtx]], [[4x9c]] – MjHfq – ''Methanococcus jannaschii''<br /> | ||
| - | **[[3hfn]] – Hfq - ''Anabaena''<br /> | ||
| - | |||
| - | *Protein Hfq complex with nucleotide | ||
| - | |||
| - | **[[3res]] – EcHfq + ADP<br /> | ||
| - | **[[3qo3]] – EcHfq + ATP<br /> | ||
| - | **[[4pno]] – EcHfq + UMP<br /> | ||
| - | **[[4j6x]] – PaHfq + UTP<br /> | ||
| - | **[[3qui]] – PaHfq + ADPNP<br /> | ||
| - | **[[4j5y]] – PaHfq + ATP<br /> | ||
| - | **[[4j6w]] – PaHfq + CTP<br /> | ||
| - | **[[2ylc]] – StHfq + UMP<br /> | ||
| - | **[[5dy9]] – MjHfq (mutant) + AMP<br /> | ||
| - | **[[4x9d]] – MjHfq + UMP<br /> | ||
| - | |||
| - | *Protein Hfq other complexes | ||
| - | |||
| - | **[[6qlb]] – EcHfq + calpain <br /> | ||
| - | **[[3vu3]] – EcHfq + catalase <br /> | ||
| - | **[[3gib]], [[4ht8]] – EcHfq + poly(A)<br /> | ||
| - | **[[4ht9]], [[5new]] – EcHfq + poly(A) + poly(U)<br /> | ||
| - | **[[3rer]] – EcHfq + poly(U) + ADP<br /> | ||
| - | **[[4qvc]], [[4qvd]] – EcHfq + RNA<br /> | ||
| - | **[[5uk7]] – EcHfq + DNA<br /> | ||
| - | **[[7ogm]] – EcHfq + PNPase + RNA – Cryo EM<br /> | ||
| - | **[[3ahu]], [[3hsb]] – Hfq + RNA – ''Bacillus subtilis''<br /> | ||
| - | **[[6o1k]], [[6o1l]], [[6o1m]] – PaHfq + Crc + RNA – Cryo EM<br /> | ||
| - | **[[4v2s]] – StHfq + sRNA<br /> | ||
| - | **[[4y91]] – Hfq + poly(U) – ''Thermotoga maritima''<br /> | ||
| - | **[[4nl3]] – LmHfq + poly(U) <br /> | ||
| - | **[[5sze]] – AaHfq + poly(U) <br /> | ||
| - | **[[1kq2]] – SaHfq + RNA <br /> | ||
| - | }} | ||
| - | |||
== References == | == References == | ||
<references/> | <references/> | ||
| - | + | </StructureSection> | |
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
| |||||||||||
