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Protein phosphatase 3D structures

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Line 9: Line 9:
**[[6dno]] - hPP1 regulatory subunit 3A + PP1A + microcystin-LR<br />
**[[6dno]] - hPP1 regulatory subunit 3A + PP1A + microcystin-LR<br />
**[[5zt0]] - hPP1 regulatory subunit 3B + PP1A<br />
**[[5zt0]] - hPP1 regulatory subunit 3B + PP1A<br />
 +
**[[7qf7]], [[7qfa]] - hPP1 regulatory subunit 3C CBM21 domain 132-264 (mutant) + cyclodextrin<br />
**[[6hkw]], [[6mky]] - hPP1 regulatory subunit 7<br />
**[[6hkw]], [[6mky]] - hPP1 regulatory subunit 7<br />
**[[6obn]], [[6obp]] - hPP1 regulatory subunit 7 + PP1-A<br />
**[[6obn]], [[6obp]] - hPP1 regulatory subunit 7 + PP1-A<br />
Line 36: Line 37:
**[[6b67]] – hPP1A (mutant) + peptide<br />
**[[6b67]] – hPP1A (mutant) + peptide<br />
**[[6alz]] – hPP1A catalytic subunit + inhibitor + Mn <br />
**[[6alz]] – hPP1A catalytic subunit + inhibitor + Mn <br />
 +
**[[8dwk]], [[8dwl]] – hPP1A catalytic subunit + E3 ubiquitin-protein ligase + Mn <br />
*Protein phosphatase 1 catalytic+regulatory subunits
*Protein phosphatase 1 catalytic+regulatory subunits
**[[5zqv]] – hPP1A catalytic subunit + regulatory subunit 3A<br />
**[[5zqv]] – hPP1A catalytic subunit + regulatory subunit 3A<br />
 +
**[[7qm2]] – hPP1A catalytic subunit (mutant) + regulatory subunit 3C (mutant)<br />
**[[4moy]], [[4mp0]] – hPP1A catalytic subunit + regulatory subunit 10<br />
**[[4moy]], [[4mp0]] – hPP1A catalytic subunit + regulatory subunit 10<br />
**[[4xpn]] – hPP1A catalytic subunit + regulatory subunit 15A<br />
**[[4xpn]] – hPP1A catalytic subunit + regulatory subunit 15A<br />
**[[6obn]], [[6obp]] – hPP1A catalytic subunit + regulatory subunit 7<br />
**[[6obn]], [[6obp]] – hPP1A catalytic subunit + regulatory subunit 7<br />
**[[6dno]] – hPP1A catalytic subunit + regulatory subunit 3A + microcystin<br />
**[[6dno]] – hPP1A catalytic subunit + regulatory subunit 3A + microcystin<br />
 +
**[[7qfb]] – hPP1A catalytic subunit + regulatory subunit 3C peptide <br />
 +
**[[7nzm]] – hPP1A catalytic subunit + regulatory subunit 15A + EIF-2A + actin – Cryo EM<br />
*Protein phosphatase 1C
*Protein phosphatase 1C
**[[4ut3]] - hPP1C + Mn<br />
**[[4ut3]] - hPP1C + Mn<br />
 +
**[[7sd0]], [[7upi]] - hPP1C catalytic subunit + SHOC-2 + MRAS + Mn – Cryo EM<br />
 +
**[[7tvf]], [[7txh]] - hPP1C catalytic subunit + SHOC-2 + MRAS + Mn<br />
*Protein phosphatase 1G
*Protein phosphatase 1G
Line 72: Line 79:
**[[7ouf]], [[7oug]], [[7pel]] – hPP2A regulatory subunit in virus intasome – Cryo EM<br />
**[[7ouf]], [[7oug]], [[7pel]] – hPP2A regulatory subunit in virus intasome – Cryo EM<br />
**[[2pkg]], [[2pf4]] – hPP2A regulatory subunit + small T antigen<br />
**[[2pkg]], [[2pf4]] – hPP2A regulatory subunit + small T antigen<br />
 +
**[[7soy]] – hPP2A catalytic subunit + PME-1 + b56gamma1 – Cryo EM<br />
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
Line 80: Line 88:
**[[4i5n]], [[4i5l]] – hPP2A catalytic + regulatory subunit + MCLR<br />
**[[4i5n]], [[4i5l]] – hPP2A catalytic + regulatory subunit + MCLR<br />
**[[3k7w]] – hPP2A catalytic + regulatory subunit + toxin<br />
**[[3k7w]] – hPP2A catalytic + regulatory subunit + toxin<br />
 +
**[[7cun]], [[7pks]] – hPP2A catalytic + regulatory subunit + integrator complex – Cryo EM<br />
**[[4iyp]] – hPP2A catalytic subunit + immunoglobin-binding protein<br />
**[[4iyp]] – hPP2A catalytic subunit + immunoglobin-binding protein<br />
**[[6ef4]] – mPP2A reglatory subunit (mutant) - mouse<br />
**[[6ef4]] – mPP2A reglatory subunit (mutant) - mouse<br />
Line 93: Line 102:
**[[3ujk]] – AtPP2C - ''Arabidopsis thaliana'' <br />
**[[3ujk]] – AtPP2C - ''Arabidopsis thaliana'' <br />
**[[4yzg]] – AtPP2C (mutant) <br />
**[[4yzg]] – AtPP2C (mutant) <br />
-
**[[3jrq]], [[3nmn]] – AtPP2C + Pyl1 + pyrabactin <br />
+
**[[3jrq]], [[3nmn]] – AtPP2C + abscisic acid receptor Pyl1 + pyrabactin <br />
-
**[[3kdj]] - AtPP2C + Pyl1 + abscicic acid<br />
+
**[[3kdj]], [[7avn]] - AtPP2C + abscisic acid receptor Pyl1 + abscicic acid<br />
-
**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br />
+
**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + abscisic acid receptor Pyl2<br />
-
**[[4la7]], [[4lg5]], [[4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br />
+
**[[4la7]], [[4lg5]], [[4lga]], [[4lgb]] – AtPP2C + abscisic acid receptor Pyl2 + ligand<br />
-
**[[5vr7]], [[5vro]], [[5vs5]], [[5vsq]], [[5vsr]], [[5vt7]] – AtPP2C + Pyl2 + quinolone derivative<br />
+
**[[5vr7]], [[5vro]], [[5vs5]], [[5vsq]], [[5vsr]], [[5vt7]] – AtPP2C + abscisic acid receptor Pyl2 + quinolone derivative<br />
-
**[[4ds8]], [[5jo1]], [[5jo2]] – AtPP2C + Pyl3 + Mn<br />
+
**[[4ds8]], [[5jo1]], [[5jo2]] – AtPP2C + abscisic acid receptor Pyl3 + Mn<br />
-
**[[3rt0]] – AtPP2C (mutant) + Pyl10<br />
+
**[[3rt0]] – AtPP2C (mutant) + abscisic acid receptor Pyl10<br />
-
**[[4n0g]] – AtPP2C + Pyl13<br />
+
**[[4n0g]] – AtPP2C + abscisic acid receptor Pyl13<br />
-
**[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C + Pyr1<br />
+
**[[3qn1]], [[3zvu]], [[4wvo]] – AtPP2C + abscisic acid receptor Pyr1<br />
-
**[[5or2]], [[5or6]] – AtPP2C + Pyr1 + abscicic acid analog<br />
+
**[[5or2]], [[5or6], [[8ay3]], [[8ay6]], [[8ay7]], [[8ay8]], [[8ay9]], [[8aya]] – AtPP2C + abscisic acid receptor Pyr1 + abscicic acid analog<br />
**[[4yzh]] – AtPP2C (mutant) + chlorophyll-binding protein peptide<br />
**[[4yzh]] – AtPP2C (mutant) + chlorophyll-binding protein peptide<br />
**[[3ujg]] - AtPP2C + SRK2E<br />
**[[3ujg]] - AtPP2C + SRK2E<br />
**[[5mn0]] – AtPP2C + ABA receptor <br />
**[[5mn0]] – AtPP2C + ABA receptor <br />
-
**[[5zch]] – PP2C + Pyl3 - rice<br />
+
**[[5zch]] – PP2C + abscisic acid receptor Pyl3 - rice<br />
*Protein phosphatase 4
*Protein phosphatase 4
Line 113: Line 122:
**[[4wsf]] – PP4 regulatory subunit + Cenp-C – ''Drosophila melanogaster''<br />
**[[4wsf]] – PP4 regulatory subunit + Cenp-C – ''Drosophila melanogaster''<br />
-
*Protein phosphatase 5
+
*Protein phosphatase 5 or Protein phosphatase T
**[[1wao]] – hPP5 + Mn<br />
**[[1wao]] – hPP5 + Mn<br />
**[[5muf]] – hPP5 <br />
**[[5muf]] – hPP5 <br />
 +
**[[7zr5]] – hPP5 + Hsp90 + CDC37 – Cryo EM<br />
 +
**[[7zr6]] – hPP5 + Hsp90 + CDC37 + Braf – Cryo EM<br />
 +
**[[8gae]], [[8gft]] – hPP5 + Hsp90 + CDC37 + Craf – Cryo EM<br />
**[[1a17]] – hPP5 protein-interacting domain<br />
**[[1a17]] – hPP5 protein-interacting domain<br />
**[[2bug]] – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR<br />
**[[2bug]] – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR<br />

Revision as of 10:25, 20 September 2023

3D Structures of protein phosphatase

Updated on 20-September-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Protein phosphatase 1 regulatory subunit
    • 5zqv - hPP1 regulatory subunit 3A + PP1A - human
    • 6dno - hPP1 regulatory subunit 3A + PP1A + microcystin-LR
    • 5zt0 - hPP1 regulatory subunit 3B + PP1A
    • 7qf7, 7qfa - hPP1 regulatory subunit 3C CBM21 domain 132-264 (mutant) + cyclodextrin
    • 6hkw, 6mky - hPP1 regulatory subunit 7
    • 6obn, 6obp - hPP1 regulatory subunit 7 + PP1-A
    • 5huz - hPP1 regulatory subunit 12A - NMR
    • 6zv2 – hPP1A regulatory subunit 10 N-terminal - NMR
    • 7nxv – hPP1A regulatory subunit 15A + actin + DNase I
    • 4xpn - hPP1 regulatory subunit 15A + PP1A
    • 2rlt - PP1 regulatory subunit 14A - pig - NMR
    • 6vti - PP1 regulatory subunit 1G N-terminal - rat - NMR
    • 4v0u - mPP1 regulatory subunit 15B + PP1G + actin + ATP - mouse
  • Protein phosphatase 1A catalytic subunit 1-330
    • 3fxj, 3fxk, 3fxl, 3fxm, 3fxo, 4mov – hPP1A + Mn
    • 6obs – hPP1A (mutant) + Mn
    • 6g0j, 6g0i – hPP1A + Fe
    • 6zk6 – hPP1A catalytic subunit (mutant) + Mn + Fe
    • 6alz – hPP1A catalytic subunit + inhibitor + Mn
    • 3n5u – hPP1A + retinoblastoma-associated protein
    • 4g9j, 5ioh – hPP1A + peptide
    • 6obq, 6obr, 6obu – hPP1A catalytic subunit + microcystin
    • 5ioh – hPP1A catalytic subunit + cell division cycle-associated protein
    • 6czo – hPP1A catalytic subunit + CASC5 protein
    • 6ghm – hPP1A catalytic subunit + ASPP2
    • 6dcx – hPP1A catalytic subunit + RelA-associated inhibitor
    • 6zee, 6zef – hPP1A catalytic subunit + Phactr1
    • 6b67 – hPP1A (mutant) + peptide
    • 6alz – hPP1A catalytic subunit + inhibitor + Mn
    • 8dwk, 8dwl – hPP1A catalytic subunit + E3 ubiquitin-protein ligase + Mn
  • Protein phosphatase 1 catalytic+regulatory subunits
    • 5zqv – hPP1A catalytic subunit + regulatory subunit 3A
    • 7qm2 – hPP1A catalytic subunit (mutant) + regulatory subunit 3C (mutant)
    • 4moy, 4mp0 – hPP1A catalytic subunit + regulatory subunit 10
    • 4xpn – hPP1A catalytic subunit + regulatory subunit 15A
    • 6obn, 6obp – hPP1A catalytic subunit + regulatory subunit 7
    • 6dno – hPP1A catalytic subunit + regulatory subunit 3A + microcystin
    • 7qfb – hPP1A catalytic subunit + regulatory subunit 3C peptide
    • 7nzm – hPP1A catalytic subunit + regulatory subunit 15A + EIF-2A + actin – Cryo EM
  • Protein phosphatase 1C
    • 4ut3 - hPP1C + Mn
    • 7sd0, 7upi - hPP1C catalytic subunit + SHOC-2 + MRAS + Mn – Cryo EM
    • 7tvf, 7txh - hPP1C catalytic subunit + SHOC-2 + MRAS + Mn
  • Protein phosphatase 1G
    • 4ut2 - hPP1G catalytic subunit
    • 5inb, 5j28 - hPP1G catalytic subunit + peptide
    • 4v0v, 4v0w, 4v0x - mPP1G catalytic subunit + hPP1 regulatory subunit 15B peptide
    • 4v0u – mPP1G catalytic subunit + regulatory subunit 15B + actin + Mn + ATP
  • Protein phosphatase 1K
    • 4da1 - hPP1K + Mn
    • 6ak7 – hPP1K (mutant) + Mg
  • Protein phosphatase 2A or serine/threonine-protein phosphatase 2A
    • 1b3u, 2g62, 2hv6, 4mew, 4i5k, 4i5j, 2jak, 2ixm, 2hv7 – hPP2A regulatory subunit
    • 5swf, 5k6s, 5jja – hPP2A regulatory subunit + BUBR1
    • 5sw9 – hPP2A regulatory subunit + RepoMan
    • 6toq – hPP2A regulatory subunit + pol protein
    • 6voy – hPP2A regulatory subunit + DNA-binding protein DNA - Cryo EM
    • 6oyl – hPP2A regulatory subunit + KIF4A
    • 6vro – hPP2A regulatory subunit + AIM1
    • 7ouf, 7oug, 7pel – hPP2A regulatory subunit in virus intasome – Cryo EM
    • 2pkg, 2pf4 – hPP2A regulatory subunit + small T antigen
    • 7soy – hPP2A catalytic subunit + PME-1 + b56gamma1 – Cryo EM
    • 2ie3, 2ie4, 2npp, 2nyl, 2nym – hPP2A catalytic + regulatory subunit + tumor-inducing toxin
    • 3c5w – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase
    • 6nts – hPP2A catalytic + regulatory subunit + activator – Cryo EM
    • 3p71, 2iae – hPP2A catalytic + regulatory subunit + LCMT-1
    • 3dw8 – hPP2A catalytic + regulatory subunit (mutant) + LCMT-1
    • 3fga – hPP2A catalytic + regulatory subunit + LCMT-1 + SGO
    • 4i5n, 4i5l – hPP2A catalytic + regulatory subunit + MCLR
    • 3k7w – hPP2A catalytic + regulatory subunit + toxin
    • 7cun, 7pks – hPP2A catalytic + regulatory subunit + integrator complex – Cryo EM
    • 4iyp – hPP2A catalytic subunit + immunoglobin-binding protein
    • 6ef4 – mPP2A reglatory subunit (mutant) - mouse
    • 5w0w – mPP2A + TIPRL
  • Protein phosphatase 2C
    • 2iq1 – hPP2C κ
    • 4ra2, 4raf, 4rag - hPP2C α (mutant) + Mn
    • 3d8k – PP2C – Toxoplasma gondii
    • 3ujk – AtPP2C - Arabidopsis thaliana
    • 4yzg – AtPP2C (mutant)
    • 3jrq, 3nmn – AtPP2C + abscisic acid receptor Pyl1 + pyrabactin
    • 3kdj, 7avn - AtPP2C + abscisic acid receptor Pyl1 + abscicic acid
    • 3nmt, 3kb3, 3nmv, 3ujl – AtPP2C + abscisic acid receptor Pyl2
    • 4la7, 4lg5, 4lga, 4lgb – AtPP2C + abscisic acid receptor Pyl2 + ligand
    • 5vr7, 5vro, 5vs5, 5vsq, 5vsr, 5vt7 – AtPP2C + abscisic acid receptor Pyl2 + quinolone derivative
    • 4ds8, 5jo1, 5jo2 – AtPP2C + abscisic acid receptor Pyl3 + Mn
    • 3rt0 – AtPP2C (mutant) + abscisic acid receptor Pyl10
    • 4n0g – AtPP2C + abscisic acid receptor Pyl13
    • 3qn1, 3zvu, 4wvo – AtPP2C + abscisic acid receptor Pyr1
    • 5or2, [[5or6], 8ay3, 8ay6, 8ay7, 8ay8, 8ay9, 8aya – AtPP2C + abscisic acid receptor Pyr1 + abscicic acid analog
    • 4yzh – AtPP2C (mutant) + chlorophyll-binding protein peptide
    • 3ujg - AtPP2C + SRK2E
    • 5mn0 – AtPP2C + ABA receptor
    • 5zch – PP2C + abscisic acid receptor Pyl3 - rice
  • Protein phosphatase 4
    • 6r8i – PP4 regulatory subunit + peptide
    • 4wsf – PP4 regulatory subunit + Cenp-C – Drosophila melanogaster
  • Protein phosphatase 5 or Protein phosphatase T
    • 1wao – hPP5 + Mn
    • 5muf – hPP5
    • 7zr5 – hPP5 + Hsp90 + CDC37 – Cryo EM
    • 7zr6 – hPP5 + Hsp90 + CDC37 + Braf – Cryo EM
    • 8gae, 8gft – hPP5 + Hsp90 + CDC37 + Craf – Cryo EM
    • 1a17 – hPP5 protein-interacting domain
    • 2bug – hPP5 protein-interacting domain (mutant) + Hsp90 peptide - NMR
    • 1s95, 3h60 – hPP5 catalytic domain + Mn
    • 3h61, 3h62, 3h63, 3h64, 3h66, 3h67, 3h68, 3h69, 4zvz, 4zx2, 4zvz, 4zx2, 5ui1 – hPP5 catalytic domain + inhibitor + Mn
    • 5wg8 – hPP5 catalytic domain + cancer drug + Mn
    • 5hpe – hPP5 catalytic domain/Hsp90 peptide + Mn
    • 4ja7, 4ja9 - rPP5 catalytic domain + inhibitor
    • 3icf - yPP5 catalytic domain + Fe - yeast
    • 5jjt – AtPP5 + Ni
    • 7obe – AtPP5 + Mn
  • Protein phosphatase
    • 1g5b – PP + Mn – Enterobacteria phage λ
    • 2pk0 – PP + Mg – Streptococcus agalactiae
    • 2cm1 – PP + Mn – Mycobacterium tuberculosis
    • 3pu9 – PP + Mg – Sphaerobacter thermophilus
    • 5f1m – PP Stp1 + Mn – Staphylococcus aureus
    • 5jpe – CaPP Z1 + Mn – Candida albicans
    • 5jpf – CaPP Z1 + microcystin-LR + Mn

}}

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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