8ec6

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Current revision (14:40, 20 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8ec6 is ON HOLD until Paper Publication
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==Cryo-EM structure of the Glutaminase C core filament (fGAC)==
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<StructureSection load='8ec6' size='340' side='right'caption='[[8ec6]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ec6]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EC6 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ec6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ec6 OCA], [https://pdbe.org/8ec6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ec6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ec6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ec6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLSK_MOUSE GLSK_MOUSE] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain.<ref>PMID:16641247</ref> <ref>PMID:22373647</ref> <ref>PMID:22228304</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Ambrosio AL]]
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[[Category: Cassago A]]
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[[Category: Dias SM]]
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[[Category: Islam Z]]
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[[Category: Portugal RV]]
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[[Category: Quesnay JE]]
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[[Category: Rodrigues CT]]
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[[Category: Van Heel MG]]

Current revision

Cryo-EM structure of the Glutaminase C core filament (fGAC)

PDB ID 8ec6

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