1mvp

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[[Image:1mvp.gif|left|200px]]
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{{Structure
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mvp OCA], [http://www.ebi.ac.uk/pdbsum/1mvp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mvp RCSB]</span>
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'''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''
'''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''
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[[Category: Ohlendorf, D H.]]
[[Category: Ohlendorf, D H.]]
[[Category: Salemme, F R.]]
[[Category: Salemme, F R.]]
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[[Category: hydrolase(aspartic proteinase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:46:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:21:50 2008''
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Revision as of 22:46, 2 May 2008

Image:1mvp.gif

Template:STRUCTURE 1mvp

STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS


Overview

The structure of the retroviral proteinase from avian myeloblastosis associated virus (MAV) has been determined and refined at 2.2 A resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase-inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases.

About this Structure

1MVP is a Single protein structure of sequence from Avian myeloblastosis associated virus. Full crystallographic information is available from OCA.

Reference

Structural studies of the retroviral proteinase from avian myeloblastosis associated virus., Ohlendorf DH, Foundling SI, Wendoloski JJ, Sedlacek J, Strop P, Salemme FR, Proteins. 1992 Nov;14(3):382-91. PMID:1332025 Page seeded by OCA on Sat May 3 01:46:37 2008

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