5jlg

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Current revision (18:57, 20 September 2023) (edit) (undo)
 
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<StructureSection load='5jlg' size='340' side='right'caption='[[5jlg]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='5jlg' size='340' side='right'caption='[[5jlg]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jlg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JLG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JLG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jlg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JLG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6L6:METHYL+(2Z)-3-HYDROXY-3-(3-HYDROXYPHENYL)PROP-2-ENE(DITHIOATE)'>6L6</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RU:RUTHENIUM+ION'>RU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASE1, RNS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6L6:METHYL+(2Z)-3-HYDROXY-3-(3-HYDROXYPHENYL)PROP-2-ENE(DITHIOATE)'>6L6</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RU:RUTHENIUM+ION'>RU</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jlg OCA], [https://pdbe.org/5jlg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jlg RCSB], [https://www.ebi.ac.uk/pdbsum/5jlg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jlg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jlg OCA], [http://pdbe.org/5jlg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jlg RCSB], [http://www.ebi.ac.uk/pdbsum/5jlg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jlg ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pancreatic ribonuclease]]
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[[Category: Ferraro G]]
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[[Category: Ferraro, G]]
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[[Category: Merlino A]]
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[[Category: Merlino, A]]
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[[Category: Hydrolase]]
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[[Category: Protein-ru compound adduct]]
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[[Category: Ruthenated protein]]
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Current revision

The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand

PDB ID 5jlg

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OCA

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